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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFS1 All Species: 54.55
Human Site: S383 Identified Species: 92.31
UniProt: Q9Y697 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y697 NP_066923.3 457 50196 S383 S S G S A C T S A S L E P S Y
Chimpanzee Pan troglodytes XP_001165456 457 50158 S383 S S G S A C T S A S L E P S Y
Rhesus Macaque Macaca mulatta XP_001097983 457 50117 S383 S S G S A C T S A S L E P S Y
Dog Lupus familis XP_534405 457 50277 S383 S S G S A C T S A S L E P S Y
Cat Felis silvestris
Mouse Mus musculus Q9Z1J3 451 49983 S377 S S G S A C T S A S L E P S Y
Rat Rattus norvegicus Q99P39 451 49994 S377 S S G S A C T S A S L E P S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026018 445 49074 S371 S S G S A C T S A S L E P S Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038458 451 50210 S377 S S G S A C T S A S L E P S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKD3 462 51056 S388 S S G S A C T S A S L E P S Y
Honey Bee Apis mellifera XP_393524 423 46979 A350 S G S A C T S A S L E P S Y V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789397 779 88565 S705 S S G S A C T S A S L E P S Y
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001148578 451 49661 S377 S S G S A C T S A S L E P S Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O49543 453 50277 S379 S S G S A C T S A S L E P S Y
Baker's Yeast Sacchar. cerevisiae P25374 497 54449 S423 S S G S A C T S A S L E P S Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.6 94 N.A. 90.8 91.4 N.A. N.A. 80.9 N.A. 74.4 N.A. 69 68.7 N.A. 46.6
Protein Similarity: 100 99.3 99.3 96 N.A. 94.3 95.4 N.A. N.A. 87.3 N.A. 84.6 N.A. 81.5 80.9 N.A. 52.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. 100 6.6 N.A. 100
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. 100 33.3 N.A. 100
Percent
Protein Identity: N.A. 66.9 N.A. 60.6 57.7 N.A.
Protein Similarity: N.A. 80.3 N.A. 74.6 71 N.A.
P-Site Identity: N.A. 100 N.A. 100 100 N.A.
P-Site Similarity: N.A. 100 N.A. 100 100 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 93 0 0 8 93 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 8 93 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 8 93 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 93 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 8 93 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 8 93 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 100 93 8 93 0 0 8 93 8 93 0 0 8 93 0 % S
% Thr: 0 0 0 0 0 8 93 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 93 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _